Instruction for Biosafety Declaration

General Advice

If you activate the checkbox for “Use of biological agents” (at beamline or in BSL-2 bio laboratory) make sure you mention ALL biological substances not being listed at Declaration of Substances.

Follow the scheme:

Biological agents	> at Biosafety Registration

All other substances and samples to be used (e.g. medium, sera, supplements, solvents, dry ice)	> Declaration of Substances

For a registration please submit the following details for EACH biological agent:

Type of agent

Cells, bacteria, sera, viruses, proteins etc.

Risk Groups following the German Biological Agents Regulations (Biostoffverordnung):

1 - Agents that are not associated with disease in healthy adult humans. This group includes a list of animal viral etiologic agents in common use. These agents represent no or little risk to an individual and no or little risk to the community.

2 - Agents that are associated with human disease which is rarely serious and for which preventive or therapeutic interventions are often available. These agents represent a moderate risk to an individual but a low risk to the community.

3 - Agents that are associated with serious or lethal human disease for which preventive or therapeutic interventions may be available. These agents represent a high risk to an individual but a low risk to the community.

4 - Agents that are likely to cause serious or lethal human disease for which preventive or therapeutic interventions are not usually available. These agents represent a high risk to the individual and a high risk to the community.

Vendor

State if you are using commercially available agents (ID, certificates) or if the agents have another source (primary cells, cooperation partners etc.). Provide also an information if the agents are deactivated (PFA, Radiation, Ethanol etc.).

The Biolab L045 at PETRA III (047c) and all experimental hutches are classified as BSL-2 for handling agents of RG2. If you transfer your probes from the lab to an experimental hutch remind that you are obligated to transport and measure S2 probes (only genetically modified organisms) only in a sealed container. Modification and manipulation are only allowed within the BSL-2 lab AFTER the on-site instruction under German genetic engineering law (GenTG/GenTSV).

For further questions please contact us on photon-science.safety-managers@desy.de